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The blood-brain barrier (BBB) is a functional structure of the brain that regulates the penetration into the Central nervous system of many foreign, toxic substances and compounds that penetrate into the blood or formed in the body itself, including drugs that can harm the nerve cells of the brain and spinal cord. BBB is not an insurmountable barrier separating the Central nervous system from the General internal environment. Its impermeability depends on the concentration and amount of substances in the blood, as...