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The aim of the present study is to investigate the biological effects of contaminants is a combination of chemical and biological measurements. Among biological measurements, investigation of alteration at the cellular or sub-cellular level can provide an early-warning signal of adverse biological response before they are manifested at the population and community level. Lysosome destabilization test has been the method of choice in the present paper. A relatively low retention time of the used red neutral dye amo...