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We present herein a thoroughly study regarding the synthesis, structure and biological activity of some hybrid diazine - polyphenols derivatives. The synthesis was performed under conventional thermal heating and microwave irradiation, by using a straight and efficient method: a N-alkylation reaction of diazine (pyridazine or phthalazine) with reactive halogenated derivatives. The structure of the hybrids was proven by elemental and spectral analysis. Under MW irradiation, the N-alkylation reaction of diazine have...

On the last few years, microwave and ultrasound irradiation has become a successful tool in modern medicinal and organic chemistry especially (but not only) because in many cases synthesis became ecologically friendly. As part of our ongoing efforts in the field of nitrogen heterocyclic derivatives, we present herein some core results obtained by our group in the field of N-alkylation and 3+2 cycloadditions reactions applied in the nitrogen heterocycles series, by using microwave and ultrasound irradiation. Compar...