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Natural gas hydrate are solid compounds formed from water (host) and gas molecules (guest) at relatively high pressure and low temperatures. They are considered as a potential alternative energy source because of their high energy density, potential carbon-neutral nature and wide existence, both in permafrost and ocean seabeds. The most developed strategies for exploiting hydrate deposits are depressurization, thermal stimulation, chemical inhibitors and CO2 replacement. In particular, chemical inhibitors promote ...