
Publication
DRUG-PEPTIDE CONJUGATES: SOLID PHASE SYNTHESIS AND MASS SPECTROMETRIC CHARACTERIZATION
(STEF92 Technology, 2021-12-20, Laura Darie‐Ion, Gabi Drochioiu, Stefania-Claudia Jitaru, Cosmin-Stefan Mocanu, Brîndușa Alina Petre)
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Peptide-drug conjugates are therapeutic agents that combine one or more drug molecules with a peptide through a biodegradable linker. Even if the peptides used in synthesis of such conjugates have a smaller pharmacological action than the small molecule of organic drug, they easily penetrate the membranes and then bind to receptors. Peptide-drug conjugates are used in various fields, such as: (i) anticancer therapy; (ii) antimicrobial application; (iii) anti-inflammatory application. In the last decades, researche...
Advances in Biotechnology2021
