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Soil saprophytic nitrogen-fixing nodule bacteria (rhizobia) of the Sinorhizobium meliloti species are formed symbiosis with alfalfa and can also be a host of bacteriophages. Rhizobia have a symbiotic and saprophytic life phase?s cycle. Nodules formed by rhizobia on alfalfa roots are destroyed at the end of the growing season and bacteria surviving in nodule threads and did not transformed into bacteroids are released into the soil microbiome. The last is enriched in bacteriophages, which can significantly decrease...

Currently, CRISPR/Cas systems are actively studied bacterial systems, due to the possibilitpossibility to apply them for targeted editing of eukaryotic genomes. CRISPR/Cas systems are belonged to adaptive immun immune system of bacteria and archaea acting against invading mobile genetic elements (MGEs: bacteriophages and integrative conjugative elements ). Curre Currently CRISPR/Cas systems were detected in genomes of 75% of known archaea and 36 % of bacteria strains . However, there are still quite less knowledge...