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In situ combustion (ISC) method is considered as a relatively inexpensive and effective method for enhanced oil recovery (EOR). It can achieve a very high oil recovery factor due to a significant increase of pressure and temperature during the combustion process of crude oil. Over the last ten years, high pressure differential scanning calorimetry (HP-DSC) has been widely used for understanding the oxidation process of heavy oil. In this paper, HP-DSC experiments were carried out to investigate the alteration of c...