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D-glucose simultaneous catalytic hydro condensation with methylamine can beconsidered a promising way of methylglucamine synthesis. Amines such asmethylamine are reacted with materials such as reducing sugars in hydroxy solventssuch as methanol to prepare N-alkyl polyhydroxy amines. Accordingly, glucose isreacted with methylamine and the resulting adduct is hydrogenated to yield N-methylglucamine. The production of N-methylglucamine as early as 1935 was patentedby American scientists Robert B. Flint and Paul L. Sa...