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The paper deals with petrology of granitoids from the Istekh ore field in northeast Yakutia accompanied by complex Au-Ag-Sn-W mineralization. Magmatism of the ore field is represented by the Istekh granitoid massif, a series of granite and rhyolite porphyry dikes, and rare dikes of diorite porphyry and trachydolerite. A polygenetic nature of the massif is documented, with origination of parental melts of the amphibole-biotite granodiorites and granites from the lower and upper crustal protoliths, respectively, und...