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COMPARATIVE ANTIOXIDANT ACTIVITY OF SOME OCULAR TISSUE LUBRICANTS FROM ROMANIAN MARKET
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S. Jurja;T. Negreanu-Pirjol;B.S. Negreanu-Pirjol
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1314-2704
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English
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17
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61
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Dry eye disease became an important problem of public health, because of its increasing incidence, caused by pollution, global warming and expanding work on video terminals. Under the actual circumstances in which the ocular tissue lubricant, commonly referred as artificial tears, market includes every day new comers, the authors were interested to find out how the various active pharmacological agents impact on the eye surface. This different impact on the eye might be able to help practitioners to better individualize artificial tears indication, for more satisfactory results on patients. The present paper emphasize the total antioxidant activity of different ocular tissue lubricants frequently commercialized on Romanian market, including four different active principles, sodium hyaluronate, hydroxypropyl-guar, hypromelose and carboxymethylcellulose, in order to find any existing correlation between the chemical characteristics and the effectiveness of an artificial tear. Comparative determination of the total antioxidant capacity of the artificial tears was quantified through photochemiluminescence method, by comparison with a standard substance specific for calibration, Trolox, as tocopherol derivative (in ACL method) using a Photochem, Analytik Jena AG apparatus. The obtained results might improve the efficiency of ocular tissue lubricant drops by revealing the different reactivity of these products under the sun influence, thus providing new criteria for the therapy selection.
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conference
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17th International Multidisciplinary Scientific GeoConference SGEM 2017
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17th International Multidisciplinary Scientific GeoConference SGEM 2017, 29 June - 5 July, 2017
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Proceedings Paper
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STEF92 Technology
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International Multidisciplinary Scientific GeoConference-SGEM
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Bulgarian Acad Sci; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Russian Acad Sci; Serbian Acad Sci & Arts; Slovak Acad Sci; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; World Acad Sci; European Acad Sci, Arts & Letters; Ac
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593-600
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29 June - 5 July, 2017
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website
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cdrom
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4427
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ocular lubricant; artificial tears; total antioxidant activity
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