Peer-reviewed articles 17,970 +



Title: EFFECT OF TECHNOLOGICAL PARAMETERS ON ELECTROSPINNABILITY OF WATER-ORGANIC SOLUTIONS OF HYALURONIC ACID

EFFECT OF TECHNOLOGICAL PARAMETERS ON ELECTROSPINNABILITY OF WATER-ORGANIC SOLUTIONS OF HYALURONIC ACID
P. P. Snetkov;T. E. Uspenskaia;M. V. Uspenskaya;K. S. Rzametov
1314-2704
English
19
6.1
Hyaluronic acid (HA) is rightfully considered as a promising and advanced polymer for development and producing a variety of applications in medicine, biotechnology and tissue engineering. One such trend is electrospun fiber materials obtained from HA solutions. However, HA has absolutely highly resistance to volatile organic solvents (such solvents are strongly encouraged for utilizing in case of electrospinning), that make the obtaining of polymer fibers difficult. Despite this, some authors could elaborate nanofibers based on HA from the aqueous-organic solutions, for instance, dimethyl formamid (DMF)/water solvent mixtures, but in the context of biomaterials utilizing DMF is prohibited. In addition, several studies describe fiber materials obtained from HA and carrier polymers such as polyvinyl alcohol (PVA) or polyethylene oxide (PEO). Having said that, utilizing such polymers notably decreases biomedical worth of native HA. This study describes the primary results of obtaining polymer structures via electrospinning from the HA solutions based on water and dimethyl sulfoxide/water systems without modifying polymers. Moreover, in this paper, the impact assessment of technological parameters on electrospinnability of spinning solutions was carried out. This finding is expected to broad the application of the electrospinning micro- and nanofibers from biopolymers for the development of modern materials.
conference
19th International Multidisciplinary Scientific GeoConference SGEM 2019
19th International Multidisciplinary Scientific GeoConference SGEM 2019, 30 June - 6 July, 2019
Proceedings Paper
STEF92 Technology
International Multidisciplinary Scientific GeoConference-SGEM
Bulgarian Acad Sci; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Russian Acad Sci; Serbian Acad Sci & Arts; Slovak Acad Sci; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; World Acad Sci; European Acad Sci, Arts & Letters; Ac
175-182
30 June - 6 July, 2019
website
cdrom
6373
biopolymer; dimethyl sulfoxide; electrospinning; hyaluronic acid; nanofibers