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Title: COMPARATIVE CHARACTERISTIC OF MULTI-ENVIRONMENTAL CARCINOGEIC RISK FOR ADOLESCENT HEALTH
COMPARATIVE CHARACTERISTIC OF MULTI-ENVIRONMENTAL CARCINOGEIC RISK FOR ADOLESCENT HEALTH

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Emiliya Valeeva; Natalya Stepanova; Gulgena Ismagilova; Oksana Sinitsyna; Galiya Skvortsova
10.5593/sgem2022/5.1/s20.014
10.5593/sgem2022/5.1
1314-2704
978-619-7603-46-0
English
22
5.1
•    Prof. DSc. Oleksandr Trofymchuk, UKRAINE 
•    Prof. Dr. hab. oec. Baiba Rivza, LATVIA
Ecology and Environmental Protection
The main aim of the work is a comparative characteristic of carcinogenic risk for the health of the adolescent and adult population from exposure to chemical contaminants on multi-environmental ingestion of chemical substances (drinking water, soil, atmospheric air, foods). A high level of total carcinogenic individual risk in the city territories under study is identified in adolescents and adults in the 2nd zone (0.00426 and 0.00298). The value of total carcinogenic risk (TCR) in the territories under study on complex multi-environmental ingestion of CSs (chemical substances) in the adolescent and the adult population corresponds to the alarming risk level (1.0 х 10-3 – 1.1 х 10-4). Chloroform and lead make the major contribution to the value of carcinogenic risk in all zones. Calculation of the carcinogenic risk levels for all carcinogenic substances was made with application of standard values and regional exposure factors at the Ме and the 95th Perc levels. Assessment of carcinogenic risk was carried out for 3 (three) substances contained in drinking water: cadmium, lead, chloroform. The total carcinogenic risk for adolescents on exposure to carcinogens contained in water REFMe and REF95 Perc was allowable in all zones. Differences in the value of carcinogenic risk levels made 0.107 – 0.227 at EFМе/SEF and 2.0 at EF 95 Реrc/SEF. The major contribution to the value of carcinogenic risk was made by chloroform and lead in all zones. We can assume that in majority of cases the main contribution is made by chloroform in the 3rd district and metals- in the 4thone. The highest carcinogenic risk level is registered at the 95th Рerc level for the adolescent health in all zones under study. Differences in regional and standard values of EF have impact on the population health risk levels. Analysis of the risk levels with application of local factors and age differences in exposure to chemicals ingested perorally with drinking water showed that the use of standard values in the methodology of risk assessment resulted in underestimation of actual carcinogenic risk for adolescents.
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This research was conducted with support from Strategic Academic Leadership Program of Kazan Federal University (PRIORITY-2030)
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https://doi.org/10.5593/sgem2022/5.1/s20.014
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Proceedings of 22nd International Multidisciplinary Scientific GeoConference SGEM 2022
22nd International Multidisciplinary Scientific GeoConference SGEM 2022, 04 - 10 July, 2022
Proceedings Paper
STEF92 Technology
International Multidisciplinary Scientific GeoConference SGEM
SWS Scholarly Society; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Serbian Acad Sci and Arts; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; European Acad Sci, Arts and Letters; Acad Fine Arts Zagreb Croatia; Croatian Acad Sci and Arts; Acad Sci Moldova; Montenegrin Acad Sci and Arts; Georgian Acad Sci; Acad Fine Arts and Design Bratislava; Turkish Acad Sci.
99-106
04 - 10 July, 2022
website
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carcinogenic risk, adolescents, adult population, chemical substances