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Title: POWER OF NANOPORE ANALYSIS FOR SUSTAINABLE AND EFFICIENT DIAGNOSTICS
POWER OF NANOPORE ANALYSIS FOR SUSTAINABLE AND EFFICIENT DIAGNOSTICS

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Luliana Soldanescu; Mihai Dimian
10.5593/sgem2023V/6.2/s25.40
10.5593/sgem2023v/6.2
1314-2704
978-619-7603-66-8
English
23
6.2
•    Prof. DSc. Oleksandr Trofymchuk, UKRAINE 
•    Prof. Dr. hab. oec. Baiba Rivza, LATVIA
Advances in Biotechnology
Nanopore technology has become widely used because of its ability to analyze molecules at an individual level, so we are seeing a dynamic development in the use of nanopores to analyze biological molecules. In 2014, the first commercial nanopore-based device capable of sequencing long strands of DNA or RNA. While the system appears to be working well, signal analysis still has barriers. The main advantage of nanopore sequencing is that it can study the structure of a single molecule and generate reads many times longer than genotyping methods. The nanopore analysis technique is low-energy and consumables are minimal, as samples in the order of tens of microliters are used, significantly reducing reagent requirements compared to traditional methods. In addition, the technique is targeted at the single molecule level, which can make it an accurate diagnostic method. Another advantage of nanopore analysis is its portability and the variety of samples that can be analyzed, making it a versatile technique for different areas of research. Using nanopores as a diagnostic tool can provide rapid diagnosis at the point of patient care without requiring significant material resources. This method is also environmentally sustainable, as it uses low levels of electricity and material waste, and could help reduce medical laboratories' environmental impact. Clinical laboratories are a factor that negatively impacts the planet's ecology, using equipment with a significant amount of electricity, chemical reagents, and disposable containers. Approaches to solving the problems are minimal, probably because it is difficult to do without certain facilities when it comes to health. We aim to highlight the importance of reducing energy and consumables consumption in medical laboratories by introducing an innovative solution, the nanopore analysis technique which has multiple benefits in terms of both medical and energy efficiency.
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This work was supported by a grant of the Ministry of Research, Innovation andDigitization, CCCDI - UEFISCDI, project number PN-III-P2-2.1-PED-2021-4380,within PNCDI III and Ministry of Research, Innovation and Digitalization withinProgram 1 - Development of National Research and Development System, Subprogram1.2 - Institutional Performance - RDI excellence funding projects, under contract no.10PFE/2021
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https://doi.org/10.5593/sgem2023V/6.2/s25.40
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Proceedings of 23rd International Multidisciplinary Scientific GeoConference SGEM 2023
23rd International Multidisciplinary Scientific GeoConference SGEM 2023, 28-30 November, 2023
Proceedings Paper
STEF92 Technology
International Multidisciplinary Scientific GeoConference-SGEM
SWS Scholarly Society; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Russian Acad Sci; Serbian Acad Sci and Arts; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; European Acad Sci, Arts and Letters; Acad Fine Arts Zagreb Croatia; Croatian Acad Sci and Arts; Acad Sci Moldova; Montenegrin Acad Sci and Arts; Georgian Acad Sci; Acad Fine Arts and Design Bratislava; Russian Acad Arts; Turkish Acad Sci.
329-326
28-30 November, 2023
website
9615
molecular analysis, portability, minimal consumables, new technology