Peer-reviewed articles 17,970 +



Title: NOVEL MATERIALS WITH MICROENCAPSULATED ESSENTIAL OILS, POTENTIAL APPLICATIONS FOR SKIN CELLULAR REGENERATION DRESSINGS

NOVEL MATERIALS WITH MICROENCAPSULATED ESSENTIAL OILS, POTENTIAL APPLICATIONS FOR SKIN CELLULAR REGENERATION DRESSINGS
Roxana Gheorghita; Roxana Filip; Andrei Lobiuc
10.5593/sgem2023v/6.2
1314-2704
English
23
6.2
•    Prof. DSc. Oleksandr Trofymchuk, UKRAINE 
•    Prof. Dr. hab. oec. Baiba Rivza, LATVIA
Biopolymers have gained notoriety due to their unique physical, chemical, and mechanical characteristics and performances. Due to their regenerability, compostability, biocompatibility, non-immunogenic, non-toxic, or non-allergenic properties, they have surpassed the boundaries of the food industry and have become fundamental components in biomedicine or the pharmaceutical industry. Thus, the most well-known applications are as drug delivery systems, tissue engineering, or wound dressings. In addition to all these characteristics, biopolymeric films have proven to be excellent matrices for incorporating various biologically active substances: natural compounds, essential oils, antioxidants, etc. The present study aimed to develop sodium alginate films, with the addition of tea tree and chamomile essential oils capsules. After development through the casting method, the materials were tested for evaluate the physical properties (thickness, retraction ratio, color, transparency, opacity), chemical properties (antioxidant characteristics), mechanical properties (tensile strength and elongation), as well as solubility (water activity index, swelling index, water absorption capacity). The results indicated that alginate based - materials with the addition of essential oils capsules can be used in the pharmaceutical and cosmetic industries for developing films with regenerative properties. Similarly, other biologically active substances can be incorporated, and the development technology can be easily scaled up to an industrial level.
[1] Das, A., Ringu, T., Ghosh, S., Pramanik, N. A comprehensive review on recentadvances in preparation, physicochemical characterization, and bioengineeringapplications of biopolymers. Polymer Bulletin, vol. 80, no. 7, 2023, pp. 7247–7312.
[2] Awasthi, S.K. et al. A comprehensive review on recent advancements inbiodegradation and sustainable management of biopolymers. EnvironmentalPollution, vol. 307, 2022, p. 119600.
[3] Shiroud Heidari, B. et al. Natural, synthetic and commercially-availablebiopolymers used to regenerate tendons and ligaments. Bioact Mater, vol. 19,2023, pp. 179–197.
[4] Aderibigbe, B.A. Hybrid-Based Wound Dressings: Combination of Synthetic andBiopolymers. Polymers, vol. 14, no. 18, 2022, p. 3806.
[5] Mohan Yallapu, M. et al. Natural Compounds and Biopolymers-Based HydrogelsJoin Forces to Promote Wound Healing. Pharmaceutics, vol. 15, no. 1, 2023, p.271.
[6] Gheorghita, D. et al. Essential Oils as Antimicrobial Active Substances in WoundDressings. Materials, vol. 15, no. 19, 2022, p. 6923.
[7] Fernandez-Quiroz, D., Tohidi, M.M., Paymard, B., Lucero-Acuna, A.Immobilization of essential oils in biopolymeric matrices: recent approaches forcontrolled delivery systems. Studies in Natural Products Chemistry, vol. 78, 2023,pp. 365–401.
[8] Pal, K., Sarkar, P., Thakur, G., Kim, D. Essential oil-loaded biopolymeric films forwound healing applications. Advances in Biomedical Polymers and Composites:Materials and Applications, 2023, pp. 541–562.
[9] Bakry, A.M. et al. Microencapsulation of Oils: A Comprehensive Review ofBenefits, Techniques, and Applications. Compr Rev Food Sci Food Saf, vol. 15,no. 1, 2016, pp. 143–182.
[10] Sousa, V.I, Parente, J. F., Marques, J.F., Forte, M.A. Tavares, C.J.Microencapsulation of Essential Oils: A Review. Polymers, vol. 14, no. 9, 2022,1730.
[11] Arenas-Jal, M., Sune-Negre, J.M., Garcia-Montoya, E. An overview ofmicroencapsulation in the food industry: opportunities, challenges, andinnovations. European Food Research and Technology, vol. 246, no. 7, 2020, pp.1371–1382.
[12] Yan, C., Kim, S.R., Ruiz, D.R., Farmer, J.R. Microencapsulation for FoodApplications: A Review. ACS Appl Bio Mater, vol. 5, no. 12, 2022, pp. 5497–5512.
[13] Hedayati, S., Tarahi, M., Azizi, R., Baeghbali, V., Ansarifar, E., Hashempur, M.H.Encapsulation of mint essential oil: Techniques and applications. Adv ColloidInterface Sci, vol. 321, 2023, 103023.
[14] Talebian, S. et al. Biopolymer-Based Multilayer Microparticles for ProbioticDelivery to Colon. Adv Healthc Mater, vol. 11, no. 11, 2022, 2102487.
[15] da F. Cardoso, L.M., Alves, L.A., Barreto, T., Gama, J.F. Natural Biopolymers asAdditional Tools for Cell Microencapsulation Applied to Cellular Therapy.Polymers vol. 14, no. 13, 2022, 2641.
[16] Yuan, Y. et al. Chemical composition, antimicrobial activities, andmicroencapsulation by complex coacervation of tea tree essential oils. J FoodProcess Preserv, vol. 46, no. 7, 2022, 16585.
[17] Hu, K. et al. Injectable carboxymethyl chitosan-genipin hydrogels encapsulatingtea tree oil for wound healing. Carbohydr Polym, vol. 301, 2023, 120348.
[18] Parveen, A., Perveen, S., Naz, F., Ahmad, M., Khalid, M. Chamomile, Essentialsof Medicinal and Aromatic Crops, 2023, pp. 1009–1040.
[19] “ASTM D882 - 18 Standard Test Method for Tensile Properties of Thin PlasticSheeting.” Accessed: Oct. 24, 2023.[Online]. Available:https://www.astm.org/Standards/D882
This work was supported by a grant of the Romanian Ministry of Research,Innovation and Digitization, CNCS/CCCDI–UEFISCDI, project number PN-III-P1-1.1-PD-2019-0793, within PNCDI III.
conference
Proceedings of 23rd International Multidisciplinary Scientific GeoConference SGEM 2023
23rd International Multidisciplinary Scientific GeoConference SGEM 2023, 28-30 November, 2023
Proceedings Paper
STEF92 Technology
International Multidisciplinary Scientific GeoConference-SGEM
SWS Scholarly Society; Acad Sci Czech Republ; Latvian Acad Sci; Polish Acad Sci; Russian Acad Sci; Serbian Acad Sci and Arts; Natl Acad Sci Ukraine; Natl Acad Sci Armenia; Sci Council Japan; European Acad Sci, Arts and Letters; Acad Fine Arts Zagreb Croatia; Croatian Acad Sci and Arts; Acad Sci Moldova; Montenegrin Acad Sci and Arts; Georgian Acad Sci; Acad Fine Arts and Design Bratislava; Russian Acad Arts; Turkish Acad Sci.
483-489
28-30 November, 2023
website
9633
biopolymers, tea tree, chamomile