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THE EFFECT OF HYDROXYAPATITE NANOPARTICLES ON ALGINATE-PLGA FOAMS STABILIZATION

Maria G. Gordienko

First published: 2019-12-05https://doi.org/10.5593/sgem2019v/6.3/s08.029View metrics

Abstract

In this work hydroxyapatite (HAP) nanoparticles ranging in size from 30 to 150 nm of lamellar and rod-shaped form were obtained by controlled deposition in the presence of a stabilizer. HAP nanoparticle powder in different mass ratios was added to a mixture of biocompatible polymers (sodium alginate and PLGA), which were the dispersion medium of the emulsion. Water or an aqueous solution of sodium citrate was used as the dispersed phase. The internal structure of the matrices was studied by scanning electron microscopy. The composition and degree of crystallinity of the samples were investigated by x-ray phase analysis. The surface of the samples was studied using energy dispersive microanalysis. Assumptions are made about the nature of the HAP-polymer interaction. It has been shown that the shape, size and number of HAP nanoparticles affect the stability of the emulsion, which in turn allows control of the size, number and shape of pores in the solid composite. This fact is important for the creation of biocompatible materials for tissue engineering.

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Publication details

Title
THE EFFECT OF HYDROXYAPATITE NANOPARTICLES ON ALGINATE-PLGA FOAMS STABILIZATION
Authors
Maria G. Gordienko
Proceedings
SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings; 19th SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings19th, Nano, Bio, Green and Space: Technologies for Sustainable Future
Publisher
STEF92 Technology
Year
2019
Pages
221-228
SWS Citekey
Gordienko20198221228
ISSN
1314-2704
ISBN
978-619-7408-99-7
Language
en
Publication type
Conference Paper
Keywords
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