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ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF NEPETA X FAASSENII EXTRACTS
Abstract
This study evaluated the antioxidant and antimicrobial properties of Nepeta - faassenii (family Lamiaceae), a perennial aromatic hybrid derived from N. racemosa and N. nepetella [12]. The genus Nepeta is recognized for its essential oils rich in nepetalactones, phenolic acids, and flavonoids, which contribute to notable biological activities such as antioxidant, antimicrobial, and insect-repellent effects [3], [9], [10], [12]. The Nepeta Vegetal Extract (NVE) was obtained through ultrasonic extraction using 60 % ethanol from aerial plant parts collected at full flowering. Quantitative phytochemical analyses revealed a total polyphenol content of 15,434.92 mg GAE/kg and flavonoid content of 2,176.73 mg QE/kg, indicating a strong antioxidant capacity with 67.78 % DPPH radical inhibition [7], [12]. Antimicrobial assays against Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli and Haemophilus influenzae demonstrated selective and dose-dependent inhibition. Maximum activity was observed at 5 -L, with inhibition rates of 64.27 % for S. pyogenes, 30.86 % for S. aureus, and 107.02 % for H. influenzae, while E. coli exhibited increased sensitivity at higher volumes (49.87 % at 40 -L) [9], [10]. These results confirm that NVE possesses potent antioxidant and selective antimicrobial properties, attributable to its phenolic and terpenoid constituents [3], [9], [12], supporting its potential application as a sustainable natural source for pharmaceutical, cosmetic, and food-preservation industries.
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Constantin Lungoci 2023- Research on the biology and technology of some species of the genus Nepeta for increasing production and its quality in the conditions of the forest-steppe of Moldova-Doctoral thesis.
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