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ANTIMICROBIAL POTENTIAL OF METHANOLIC AND N-HEXANE EXTRACTS OF VISCUM ALBUM
Abstract
Plants are sources of compounds with medicinal potential, an impressive number of medicines have in their composition compounds isolated from natural sources, many of them being used since ancient times, in traditional medicine. Aromatic and medicinal plants are sources of various nutrients and non-nutritive molecules, many of which exhibit antimicrobial and antioxidant properties. V. album extracts have a complex chemical composition, some of the identified compounds being responsable for their antibacterial and antifungal potential. The chemical composition of V. album extracts differs depending on the provenance and especially with respect to the host plant. The antimicrobial effect of extracts in methanol and n-hexane from leaves and young branches of V. album was tested by the diffusimetric method on agar. In the study, five concentrations were tested for each extract, on four Gram positive bacterial strains: Streptoccoccus pyogenes, Enterococcus faecalis, Clostridium perfringens, Staphylococcos aureus and three Gram negative: Escherichia coli, Pseudomonas aeruginosa, Legionella pneumophila, respectively two antibiotics: ampicillin and chloramphenicol were used as a reference control. Gram+ and Gram- bacterial strains showed an intermediate sensitivity at the first two concentrations tested for both extracts (methanolic and n-hexane), after which the antibacterial potential decreases with the decrease in concentration until it disappears completely. The effects of the methanolic extract of V. album is more obvious in Gram+ bacteria compared to Gram-. The n-hexane extract of V. album determines an antimicrobial effect only at the first concentrations tested, there are variations depending on the bacterial strain.
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