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THE ELEMENTAL PROFILE OF THE FEMALE BODY AS A REFLECTION OF THE ELEMENTAL COMPOSITION OF THE ENVIRONMENT IN YAKUTIA
Abstract
Introduction. According to observations of Russian scientists, the complex of biomedical and ecological factors, strictly specific for components of both northern ecosystems and northern human populations, participates in the formation of human health in the North. The aim of the work is to reveal the regularity of distribution of diselementoses and the elemental profile of pathology in women from various regions of the Republic of Sakha (Yakutia). Materials and methods. Using the multielement analysis system using AES-ISP and MS-ISP methods, the content of chemical elements in the hair of 555 women from various regions of the Republic of Sakha (Yakutia) was investigated. The study of hair was conducted on the content of 24 chemical elements (Al, As, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, P, Pb, Se, Si, Sn, Ti, V, Zn , ?g / g). The analysis of the samples is carried out using the ISP-AES method using the Optima 2000 DV (PerkinElmer) instrument (determination of Ca, Mg, P, Zn, K, Na), as well as the ICP-MS method using the Elan 9000 (PerkinElmer) (Al, As, Cd , Co, Cr, Cu, Fe, Mn, Ni, Pb, Se, Si, Sn, Ti, V). Statistical processing of the data was carried out using Microsoft Excel XP and Statistica 6.0. In assessing the reliability of the differences, the value p <0.05 was used. Assessment of the reliability of the differences between the data obtained in the study groups was carried out according to Student's t-criterion. Results. As shown by the analysis of the obtained data, for women living in different regions of the Republic of Sakha (Yakutia), there are significant differences in the content of chemical elements in the hair. The observed differences are mainly due to the original ?elemental portrait? of residents of the polar and, to a greater extent, southern regions of the Republic, while the ?elemental portraits? of residents of the Western and Central regions and Yakutsk are reliable there are practically no differences and they can be considered ?average? for the surveyed region. Discussion. The results obtained when comparing the hair composition of the female population of the Central regions of the Republic of Sakha (Yakutia) and Yakutsk seem to be the result of a high degree of urbanization, which significantly changes the natural elemental balance of population groups, including women (the population of the Arctic, Western and Southern areas in the vast majority of rural). Conclusion. The results obtained show that the risk of hyperelementosis in the female population of the Republic of Sakha (Yakutia) is significantly increasing in the direction of south-south; in the direction of north-south the risk of development of hypo-elemental diseases increases significantly. At the same time, the central regions of the republic are an exception to the general scheme: the prevalence of excessive accumulation in the hair as toxic and essential chemical elements is also great here, as in the arctic regions of the republic.
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