Scholarly record
COMPARATIVE ANTIOXIDANT ACTIVITY OF SOME OCULAR TISSUE LUBRICANTS FROM ROMANIAN MARKET
Abstract
Dry eye disease became an important problem of public health, because of its increasing incidence, caused by pollution, global warming and expanding work on video terminals. Under the actual circumstances in which the ocular tissue lubricant, commonly referred as artificial tears, market includes every day new comers, the authors were interested to find out how the various active pharmacological agents impact on the eye surface. This different impact on the eye might be able to help practitioners to better individualize artificial tears indication, for more satisfactory results on patients. The present paper emphasize the total antioxidant activity of different ocular tissue lubricants frequently commercialized on Romanian market, including four different active principles, sodium hyaluronate, hydroxypropyl-guar, hypromelose and carboxymethylcellulose, in order to find any existing correlation between the chemical characteristics and the effectiveness of an artificial tear. Comparative determination of the total antioxidant capacity of the artificial tears was quantified through photochemiluminescence method, by comparison with a standard substance specific for calibration, Trolox, as tocopherol derivative (in ACL method) using a Photochem, Analytik Jena AG apparatus. The obtained results might improve the efficiency of ocular tissue lubricant drops by revealing the different reactivity of these products under the sun influence, thus providing new criteria for the therapy selection.
Publication Impact Profile
Publication details
References8
Jurja S., Negreanu–Pîrjol T., Negreanu-Pîrjol B.-Ș., Roncea F. N., UV radiation influence on the total antioxidant capacity of artificial tears (ocular lubricant), 16th International Multidisciplinary Scientific GeoConferences – SGEM 2016 - Nano, Bio and Green – Technologies for a Sustainable Future”, Albena, Bulgaria, Conference Proceedings, Vol. I, Section „Advances in Biotechnology”, p. 395 – 403, 2016.
Savini G., Prabhawasat P., Kojima T., Grueterich M., Espana E., Goto E., The challenge of dry eye diagnosis, Clin. Ophthalmol., 2(1): 31–55, 2008.
Jurja S., Negreanu–Pîrjol T., Lepadatu A.C., Sirbu R., Negreanu-Pîrjol B.-Ș., Different artificial tears, different eyes...How to choose?, 15th International Multidisciplinary Scientific GeoConferences – SGEM 2015 - Nano, Bio and Green – Technologies for a Sustainable Future”, Albena, Bulgaria, Conference Proceedings, Vol. I, Section „Advances in Biotechnology”, p. 405 – 410, 2015.
Chantanawarangoon S., Padilla-Zakour O.I., Water-soluble antioxidant capacity of phenolic compounds and Trolox using photochemiluminescence method (PCL), Poster presented at IFT- 2003 by, Food Science & Technology Cornell University of Food Science, Geneva NY.
Neudecker B.A., Bkayarov D., Wieland E., Lewis II J.A., DiNardo J.C., Maibach H.I., Antioxidants Compared in a New Protocol to Measure Protective Capacity against Oxidative Stress, Poster presented at the AAD-2003 meeting in California.
Popov I., Lewin G., Antioxidative Homeostasis: Characterization by Means of Chemiluminescent Technique, Methods in Enzymology, Volume 300, Oxidants and Antioxidants, Part B, Ed. Lester Packer, Academic Press, 437-456, 1999.
Popov I., Lewin G., Photochemiluminescent detection of antiradical activity; IV: testing of lipid-soluble antioxidants, J. Biochem. Biophys. Methods, 31, 1-8, 1996.
Popov I.N., Lewin G., Photosensitized Chemiluminescence, Labo, 8, pp. 498- 527, 1997.
View or Download full articleAccess options
SWS access login
Login as SWS Scientific CommitteeLogin as SWS Scientific PartnerLogin as SWS AuthorAuthors and approved SWS contributors will read and export their own linked papers after identity matching by SWS profile, email and SGEM GlobalID.
For librarian assistance: [email protected]
Purchase Instant Access
- Article can be downloaded after successful payment.
- Article may be used according to SWS library access terms.
- Article cannot be redistributed.
