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Sulfonamides are appropriate ligands for the preparation of coordination compounds with biological activity, as they possess bactericidal, antiviral, antidiabetic, and diuretic properties and some sulfonamide compounds are under clinical evaluation for cancer treatment. Metal complexes provide highly versatile platforms for drug design. Considering the biological potential of the quinoline nucleus, but also of the sulfonamide scaffold (especially antimicrobial), as well as that of the quinoline- sulfonamide combin...

Spectrophotometric methods for total protein analysis are generally simple, rapid and sensitive. Such sensitive protein assays may have applications in forensic science, in the detection of protein contaminants in drugs and in a number of other applications of research interest. Biuret reaction with proteins and peptides is widely used in clinical and biological laboratories. In this work, instead of copper sulphate, sodium hydroxide and Seignette salt, we used insoluble copper phosphate, potassium or sodium hydro...