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Worldwide there is a need to develop new advanced materials based on silicone elastomers with high-performance properties, reinforced with nanoparticles. The curing process as a primary step has a major impact on the properties of the final product, including the determination of the optimal amount of reinforcing agent in the nanometer range and cross-linking agent (peroxides - specific to food, pharmaceutical, medical and consumer goods industries). The aim of the study is to obtain an antibacterial elastomer com...

The objective of the study was to increase the solubility of amiodarone hydrochloride by complexation with hydroxypropyl-пїЅ-cyclodextrin. After complexation a cyclodextrin/amiodarone inclusion complex was formed. The use of media containing surfactants is a suitable solubilizing method and as a result, a non-ionic surfactant - Tween 80 and an anionic one - sodium lauryl sulfate have been used. The dissolution profile of amiodarone hydrochloride and that of the inclusion complex, regarding the release of the activ...