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THE STUDY OF SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW 1,4- DIAZINIUM DERIVATIVES
(SGEM Scientific GeoConference, 2008, M. Ungureanu, A. Poiata, C. Tuchilus, I. I. Mangalagiu)
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In previous papers, we emphasised the important antimicrobial properties of some pyrazine and quinoxaline derivatives. In order to extend the research in the 1,4-diazine series, in this study we investigate the synthesis and amtimicrobial properties of some pyrazine and 6-methyl-quinoaline new derivatives. To this stage, we synthesised various cycloimmonium salts with acetophenone skeleton. On further treatment of diazinium salts in alkaline medium, we obtained ylidic intermediates. The existence in situ of ylids ...
Ecology and Environmental Protection2008