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In this paper we present the results obtained regarding the functionalization of the surface of sheepskins using nanocomposites based on reduced graphene oxide - TiO2-Ag and reduced graphene oxide - TiO2-Cu in order to obtain leather with antimicrobial and photocatalytic properties. The nanocomposites were integrated in film forming polymer composites and were applied by spraying on sheepskin surfaces. Sheepskin surfaces were characterized using scanning electron microscopy (SEM), physico-mechanical methods, photo...