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BIOTECHNOLOGY OF BOVINE LACTOFERIN FOR MEDICAL AND DIETARY PURPOSE
(STEF92 Technology, 2017-06-20, E.I. Titov, Natali Tikhomirova, I.I. Ionova, Irina Krasnova)
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Lactoferrin (LF) is a globular glycoprotein with a molecular mass of about 80 kDa. It exists in two forms: apo- and hololactoferrin. Lactoferrin in the molecule has two domains that bind Fe3+ ions with high efficiency. The physiological properties of the protein are mainly due to binding to the iron of the active form by unsaturated iron (apolactoferrin). An iron-saturated form (hololactoferrin) is inactive. Raw milk contains mainly up to 90% apo-LF. Human milk is very rich in lactoferrin (about 1.7 g/L), and bovi...
Advances in Biotechnology2017