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The paper consider the impact of the view on petroleum origin on the strugegy its exploration. The petroleum is complex, natural Self-organizing system. Its genesis, migration and accumulation in a pool is discrete process not associated with Biosphere matter and energy. Hydrocarbon (HC) molecules are generating during their migration thought Lithosphere layers under catalytic interaction with their selves and rocks. The structure and composition of the HC molecules different type appearing during the stages of th...