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The specificity of the microelement environment in the population of individual geochemical provinces determines the features of homeostasis regulation processes. In conditions of excessive intake of strontium with drinking water, it is assumed pathological disorders of the parameters of osteometabolism with the involvement of immune regulation mechanisms. We examined 59 children of preschool age permanently residing in the territory of the strontium geochemical province and consuming drinking water with an excess...

Chemical compounds of natural origin have high biological activity, complex effects on the human body, and safety for health. Preparations based on natural plant raw materials affect the body's adaptive capabilities, acting as factors of nonspecific defense and cofactors of the immune system. The aim of the study is to evaluate the effect of phenolic constituents of plant origin on the phagocytic activity of peripheral blood cells in vitro. Materials and methods. In vitro study of the effect of phenolic constituen...

A high level of professionally determined morbidity conditiones the need to identify marker indicators of health status, immune adaptation mechanisms and markers of sensitization under conditions of exposure to harmful production factors. We examined 70 employees of the sylvinite processing plant, workers in unfavorable conditions of chemical exposure to dust of potassium chloride, saturated hydrocarbons (hexane), formaldehyde. The comparison group consisted of employees of the administrative apparatus. The formal...

Considering the high potential threat to the environment and humans caused by the components of dust and gas emissions, the aluminum industry belongs to the category of industries of increased danger to public health. Violation of the process of apoptosis control under the negative influence of environmental factors leads to homeostasis shifts and is one of the many factors contributing to the development of immune regulation disorders. This paper aims to assess the features of cell death in the adult population o...

Excess natural and technogenic chemical exposure have a negative impacts on the regulatory systems of the body. This leads to a decrease in its resistance and adaptabilities. The child`s body is the most vulnerable to the impact of adverse environmental factors owing to the age characteristics. Strontium belongs to the group of metals that can form an improper quality of drinking water, and is also included in the list of the main indicators of water quality according to the requirements of sanitary standards of t...

An immunological diagnostic examination of 255 children permanently residing in the zone of influence of exogenous haptens and the intense climate of the Arctic was performed. The control group consisted of 130 children living in the territory beyond the influence of exogenous chemical and climatogeographic factors. Determination of total serum immunoglobulins G, A, M was performed using the Mancini radial immunodiffusion reaction. The concentration of total IgE, neuron-specific enolase and VEGF was determined usi...