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To date, there is an increase in the incidence of skin and subcutaneous tissue diseases, despite the variety of treatment methods. One of the promising class of biomaterials for the treatment of skin diseases can be coatings based on hydrogels. The purpose of this study was to obtain collagen-acrylic hydrogels with various technological parameters (varying the synthesis temperature and the degree of neutralization of acrylic acid) with the specified properties by radical polymerization. The chemical structure of t...

The problem of obtaining compositions, that would act as biomaterials and fit all demands, is well-known. One the branch of application materials such is the hydrogels. High retention capacity of water and physiological fluids, sufficient physio-mechanical properties and safety of usage are ones of the most relevant specifications for medical hydrogels. It is quite hard to develop such formulations. Perspective initial substances for synthesis are gelatin (peptide native to human collagen) and tannin (natural comp...

Fabrication of nanofibers is a field of research attracting a lot of interest from technologici scientists because of its great applications in many fields. In order to design the polymer drug delivery system, we had to select a polymer that is biocompatible, biodegradable, non-toxic and approved for medical use. One of the polymers that fulfill those requirements is poly (vinyl alcohol) (PVA). There have been various reports on the fabrication of PVA nanofibers with solvents as water, or water with different salt...