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The aim of the study is to assess economic damage from real losses of the working-age population of the constituent entities of the Siberian Federal District caused by the negative impact of climate change, air pollution, man-made emergencies and transport accidents. The economic damage assessment from premature deaths of the working-age population of the Siberian Federal District was conducted based on data from the territorial offices of Rosstat, the Ministry of Emergency Situations, and medical analytical cente...