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Mihai Mares

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SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings; 17th International Multidisciplinary Scientific GeoConference SGEM2017, Nano, Bio and Green - Technologies for a Sustainable Future
Publication

A STUDY ON THE OPTIMIZATION OF ANTIMICROBIAL ACTIVITY OF ERYTHROMYCIN BY COMPLEXATION WITH ?-CYCLODEXTRIN DERIVATES

(STEF92 Technology, 2017-06-20, Lacramioara Ochiuz, Cristian Peptu, Catalina Anisoara Peptu, Anca Grigoras, Mihai Mares)

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Erythromycin (E), a hydrophobic macrolide antibiotic, is prescribed for the treatment of acute bacterial infections, such as respiratory, urine, skin, and mouth infections. The main disadvantage of ER is its poor water solubility (2 mg/mL) that limits both formulation using hydrophilic bases and skin permeability. Cyclodextrins (CDs) are biocompatible cyclic oligomers of glucose, with a hydrophobic core and a hydrophilic exterior. CDs are used to improve the bioavailability of drugs by increasing their solubility ...

Micro and Nano Technologies2017
SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings; 17th International Multidisciplinary Scientific GeoConference SGEM2017, Nano, Bio and Green - Technologies for a Sustainable Future
Publication

CHEMICAL SYNTHESIS OF NEW COMPOUNDS WITH ANTIDEPRESSANT ACTION

(STEF92 Technology, 2017-06-20, Alina Stefanache, Corneliu Oniscu, Mihai Mares, Gladiola Tantaru, Lacramioara Ochiuz)

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The present research is a part of the obtaining innovative medicine domain and is concerned with conceiving and developing new anti depressive medicines, endowed with a high therapeutically degree, low secondary effects and impact on the quality of life, through a research partnership. The impact of Borderline personality disorder (BPD) diseases, especially depression, is continuously growing and as a treatment, are used anorganic products based on lithium, such as lithium carbonate, lithium citrate or lithium oro...

Micro and Nano Technologies2017
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