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The specificity of the microelement environment in the population of individual geochemical provinces determines the features of homeostasis regulation processes. In conditions of excessive intake of strontium with drinking water, it is assumed pathological disorders of the parameters of osteometabolism with the involvement of immune regulation mechanisms. We examined 59 children of preschool age permanently residing in the territory of the strontium geochemical province and consuming drinking water with an excess...

Chemical compounds of natural origin have high biological activity, complex effects on the human body, and safety for health. Preparations based on natural plant raw materials affect the body's adaptive capabilities, acting as factors of nonspecific defense and cofactors of the immune system. The aim of the study is to evaluate the effect of phenolic constituents of plant origin on the phagocytic activity of peripheral blood cells in vitro. Materials and methods. In vitro study of the effect of phenolic constituen...

Summary. Aluminum, entering the human body, has the property of accumulation, modulates immunoregulation and metabolism, especially mineral. It also exhibits the properties of a sensitizer and neurotoxicant, mutagen and carcinogen. And in the case of aerogenic exposure, the target object is additionally the upper and lower respiratory tract system. Exposed by aluminium children are especially inclined to occurrence of negative effects. The research is aimed to study the immune status of children of primary school ...

Introduction Violations of autonomic nervous regulation are a multifactorial pathology, while environmental features are an important risk factor for this pathology. Excessive exposure to neurotropic technogenic chemical factors, including benzene, to the biological environment of the human body induces malfunctions of adaptive-compensatory mechanisms and forms an increased risk of developing disorders of autonomic regulation associated with the immune system, which are realized against the background of polymorph...

Drinking water contamination with technogenic haptens forms an imbalance in the adaptive capabilities of the immune system in children. The aim of this work is to study the features of laboratory markers of the cytokine profile in children, probabilistically associated with an increased content of chloroform in the blood. Materials and methods. The study involved 283 children living in conditions of chronic low-level oral exposure to hyperchlorination products of drinking water, the control for which was a conting...

Today, the analysis of the unique contribution to the formation of the ?genetic portrait? of regional features, including technogenic ones, which determines the occurrence of diseases and harm to health, is relevant. The use of modern critical genetic and cellular biotechnologies with the study of genetic polymorphism and thin cell subpopulations will allow us to catch the earliest violations of homeostatic indicators in geochemical technogenic provinces. The aim of the work is to assess the features of genetic in...