Browse

An environmentally safe method - metal-vapor synthesis (MVS), was applied to produce iron nanoparticles (Fe NPs), which were conjugated with the drug methotrexate (MTX). The physicochemical properties and biological activity of the generated Fe NPs-MTX nanomaterials were analyzed. Transmission electron microscopy observations indicated that Fe NPs are stabilized in the form of aggregates with a size of 100 nm. The structure of these aggregates is similar to a -bunch of grapes-, which consists of metal particles ab...

Gold and iron nanoparticles were generated via environmentally safe metal-vapor synthesis method applying acetone or toluene as organic dispersion medium. Biological properties of the nanoparticles were analyzed by the agar disc diffusion method using Gram-positive and Gram-negative bacteria and via in vitro cytotoxicity assays with different human cell lines. The obtained results revealed distinct biological activity profiles of the studied specimens. Fe nanoparticles (Fe NPs) demonstrated inhibitory effects agai...

New hybrid materials based on copper nanoparticles stabilized in an ultimately biocompatible chitosan matrix were prepared via metal vapor synthesis. Transmission electron microscopy shows that the particles have predominantly spherical form, polydisperse character, the mean diameter about 2-4 nm and a rather uniform distribution in the chitosan matrice. X-ray photoelectron spectroscopy of Cu-carrying chitosan powder obtained by impregnation of chitosan powder with Cu-acetone organosol indicated two oxidized coppe...