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Chamomile flower, a well-known medicinal plant, possesses significant antioxidant properties attributed to its diverse array of bioactive compounds, including antioxidant proteins. These proteins are vital in combating oxidative stress and neutralizing harmful free radicals. To fully harness the antioxidant potential of chamomile, it is imperative to optimize the extraction methods. This study evaluates the effectiveness of nonconventional mechanical extraction methods using ultrasound to extract antioxidant compo...

Harvested bee pollen has been used since ancient times for its healthy properties and nutritional value. In terms of composition, bee pollen contains a large number of different substances such as proteins, carbohydrates and lipids as well as phenolic organic compounds. The protein content is the second most abundant component, its levels (10 to 40%, w/w) depending on the type of plant. Recently, numerous studies have demonstrated the beneficial properties of pollen in promoting health and reducing the risk of dev...

Peptide-drug conjugates are therapeutic agents that combine one or more drug molecules with a peptide through a biodegradable linker. Even if the peptides used in synthesis of such conjugates have a smaller pharmacological action than the small molecule of organic drug, they easily penetrate the membranes and then bind to receptors. Peptide-drug conjugates are used in various fields, such as: (i) anticancer therapy; (ii) antimicrobial application; (iii) anti-inflammatory application. In the last decades, researche...

Alzheimer?s disease, the most common age-related dementia worldwide, is characterized by two pathologies: deposition of ?-amyloid plaque and neurofibrillary tangles of hyperphosphorylated tau. To this date, several factors, such as oxidative stress, metal ions, or genetic factors are associated with Alzheimer`s diseases, but there are still some question marks regarding: (i) how the misfolding and aggregation of A? occurs and which is the aggregation mechanism; (ii) how the metal ions binds to A? and how they init...